Skeleton .. endless
secrets.
Scientists
are discovering that the skeleton has to do with sex and diabetes, scientists
have believed for years, they understand the skeleton, they said, he was working
as a structural support for the body, and stores of calcium and phosphate and
contribute to the development of blood cells. It is an
integral part of 'spells' against terrifying things. But secrets do not
end
Complex links between the skeleton and sugar and sex
* But it turns out that there are probably many, many benefits for the bones, discovered a few years ago, researchers at Columbia University Medical Center, the skeleton helps regulate blood sugar. The recently discovered group, headed by Dr. Gerard كارسينتي specialist genetics and endocrinology at Columbia University, that the bones play an unexpected role in the reproductive process and it is possible that this work will help, if its development, to explain some cases of low fertility in men.
Said Dr. William Crowley at the Harvard School of Medicine, who was not involved in this research, in talking about the new findings on fertility «These results certainly attracts attention. I think it will be a seminal observation. (It seems that he did not deliberately play on words).
It is known that hormones estrogen and testosterone, produced by the ovaries and testes respectively, help regulate bone growth. When women reach menopause, less estrogen levels, as well as bone density, which increases their risk of osteoporosis. As the men in the age, lower the level of testosterone and estrogen also. The men's bones, but loses more slowly than women.
And said كارسينتي «We thought that if I spoke genital skeleton, the skeleton must be talking to the sexual organs also. This seems to be what is happening.At the beginning of this year, team كارسينتي published study explains that protein osteocalcin in mice, a protein produced by the bone-forming cells that called Ostjublast, is linked to the future of a specific neurotransmitter in testicular cells. And produced male mice that were not able to work osteocalcin (as a result of genetic manipulation) less testosterone and were less fertile. When the mating, had fewer and smaller offspring.
On the other hand, were not affected fertility in female mice Balawstioukalcin. Has missed cells Mbaeidaha to nerve receptors associated bone hormone. And said كارسينتي «We were surprised with this result. We believe we have found a hormone regulates fertility in both sexes. He added, there is another compound, is unknown, it is possible to play a similar role in females. The كارسينتي found that human testicular cells also include neurological receptors hormone Alawsticalsin.
Said Thomas Clemens, a researcher at Johns Hopkins University «I do not know if there was a role hormone in mice but has no role in humans. It is not possible identical to the importance of this effect in humans with its importance in mice.
The main hormone that works to stimulate the production of testosterone, in mice and men, is a hormone LH, a protein produced by the brain. The LH is the key hormone testosterone operating, according to Crowley. On the other hand, hormone Alawsticalsin, it looks more like a reduced right light that adjusts the process.
* The role of the bones and the question arises, is it a vital mechanism or backup system? Does osteocalcin plays a widespread problems such as the small number of sperm or low rate of testosterone or whether it plays a secondary role?The scientists now plan to study men with these problems and measure Alausticalcen levels, according to Crowley. Perhaps some of these men infected defect in Alawsticalsin or future nervous him hide behind these cases. But he said «I doubt that this will turn into one of the chapters of this interesting and complex puzzle.
The كارسينتي said that bones play a major role in regulating the body's physiological. He said «The body is not a grouping of silos that do not talk to each other but it is full of amazing examples for crosstalk.In 2007, he explained that the bones helps regulate blood sugar, a result that stunned the hormones professionals. As mentioned that Alawsticalsin enhances insulin production in the pancreas and increases insulin sensitivity (which makes the body more responsive to the hormone). Insulin works, in turn, reduce blood sugar.
It is possible that this work is linked to diabetes, where the body does not produce enough insulin or stop responding to its directions. As a result, the blood glucose level rises significantly.The كارسينتي now hopes to reveal the complex ties that bind between the skeleton and sugar and sex. He pointed out that osteoporosis decline with age, as is the case for control blood sugar and fertility. He mentioned that there is an idea to suggest that the bones do not be a victim of progress in life but also contribute in this matter.
Complex links between the skeleton and sugar and sex
* But it turns out that there are probably many, many benefits for the bones, discovered a few years ago, researchers at Columbia University Medical Center, the skeleton helps regulate blood sugar. The recently discovered group, headed by Dr. Gerard كارسينتي specialist genetics and endocrinology at Columbia University, that the bones play an unexpected role in the reproductive process and it is possible that this work will help, if its development, to explain some cases of low fertility in men.
Said Dr. William Crowley at the Harvard School of Medicine, who was not involved in this research, in talking about the new findings on fertility «These results certainly attracts attention. I think it will be a seminal observation. (It seems that he did not deliberately play on words).
It is known that hormones estrogen and testosterone, produced by the ovaries and testes respectively, help regulate bone growth. When women reach menopause, less estrogen levels, as well as bone density, which increases their risk of osteoporosis. As the men in the age, lower the level of testosterone and estrogen also. The men's bones, but loses more slowly than women.
And said كارسينتي «We thought that if I spoke genital skeleton, the skeleton must be talking to the sexual organs also. This seems to be what is happening.At the beginning of this year, team كارسينتي published study explains that protein osteocalcin in mice, a protein produced by the bone-forming cells that called Ostjublast, is linked to the future of a specific neurotransmitter in testicular cells. And produced male mice that were not able to work osteocalcin (as a result of genetic manipulation) less testosterone and were less fertile. When the mating, had fewer and smaller offspring.
On the other hand, were not affected fertility in female mice Balawstioukalcin. Has missed cells Mbaeidaha to nerve receptors associated bone hormone. And said كارسينتي «We were surprised with this result. We believe we have found a hormone regulates fertility in both sexes. He added, there is another compound, is unknown, it is possible to play a similar role in females. The كارسينتي found that human testicular cells also include neurological receptors hormone Alawsticalsin.
Said Thomas Clemens, a researcher at Johns Hopkins University «I do not know if there was a role hormone in mice but has no role in humans. It is not possible identical to the importance of this effect in humans with its importance in mice.
The main hormone that works to stimulate the production of testosterone, in mice and men, is a hormone LH, a protein produced by the brain. The LH is the key hormone testosterone operating, according to Crowley. On the other hand, hormone Alawsticalsin, it looks more like a reduced right light that adjusts the process.
* The role of the bones and the question arises, is it a vital mechanism or backup system? Does osteocalcin plays a widespread problems such as the small number of sperm or low rate of testosterone or whether it plays a secondary role?The scientists now plan to study men with these problems and measure Alausticalcen levels, according to Crowley. Perhaps some of these men infected defect in Alawsticalsin or future nervous him hide behind these cases. But he said «I doubt that this will turn into one of the chapters of this interesting and complex puzzle.
The كارسينتي said that bones play a major role in regulating the body's physiological. He said «The body is not a grouping of silos that do not talk to each other but it is full of amazing examples for crosstalk.In 2007, he explained that the bones helps regulate blood sugar, a result that stunned the hormones professionals. As mentioned that Alawsticalsin enhances insulin production in the pancreas and increases insulin sensitivity (which makes the body more responsive to the hormone). Insulin works, in turn, reduce blood sugar.
It is possible that this work is linked to diabetes, where the body does not produce enough insulin or stop responding to its directions. As a result, the blood glucose level rises significantly.The كارسينتي now hopes to reveal the complex ties that bind between the skeleton and sugar and sex. He pointed out that osteoporosis decline with age, as is the case for control blood sugar and fertility. He mentioned that there is an idea to suggest that the bones do not be a victim of progress in life but also contribute in this matter.
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